VACCINATION WITH LIPID CORE PEPTIDES FAILS TO INDUCE EPITOPE-SPECIFIC T CELL RESPONSES BUT CONFERS NON-SPECIFIC PROTECTIVE IMMUNITY IN A MALARIA MODEL.

Vaccination with lipid core peptides fails to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.

Vaccines against many pathogens for which conventional approaches have failed remain an unmet public health priority.Synthetic peptide-based vaccines offer an attractive alternative to whole protein and whole organism vaccines, particularly for complex pathogens that cause chronic infection.Previously, we have reported a promising lipid core peptid

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Clinical approaches for poststroke seizure: a review

Poststroke seizure is a potential complication of stroke, which is the most frequent acute symptomatic seizure in adults.Patients with stroke may present with an abnormal or aggressive behavior accompanied by altered mental status and symptoms, such as hemiparesis, dysarthria, and sensory deficits.Although stroke manifestations that mimic seizures

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Mud binds the kinesin-14 Ncd in Drosophila

Maintenance of proper mitotic spindle structure is necessary for error-free chromosome segregation and cell division.Spindle assembly is controlled by force-generating kinesin motors that contribute to its geometry and bipolarity, and balancing motor-dependent forces between opposing kinesins is critical to the integrity of this process.Non-claret

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